Are There Any Negative Side Effects From Molecular Hydrogen Water?

A Group Of Scientists Examining Hydrogen Water

So, Are There Any Negative Side Effects From Molecular Hydrogen Water?

Short answer: very very rarely, its highly unlikely that you will have any negative side effects from molecular hydrogen water. Very few minor side effects have been reported and usually due to other factors at play. After extensive analysis, we can confidently state that molecular hydrogen water has an exceptional safety profile with minimal reported side effects. In fact, out of numerous clinical trials involving thousands of participants, only a handful of potential adverse events have been documented.


Molecular Hydrogen Water And HeadachesWoman with Headache

In an open-label metabolic syndrome study that recorded most adverse events, a single incident of headache was reported. While a headache report may not seem surprising, the rarity of such occurrences is noteworthy.


Molecular Hydrogen Water And Lactose Intolerance 

While excess hydrogen gas from lactose intolerance can cause gut issues like Irritable bowl syndrome, the relationship between hydrogen and gut health is complex.

Surprisingly, molecular hydrogen therapy shows promise for inflammatory bowel diseases and ulcerative colitis. This paradox highlights how some individuals may benefit from interventions involving exogenous hydrogen gas consumption, while others may not respond as well.

 Human Anatomy

Molecular Hydrogen Water And Cardiac Failure

In a single report, a patient undergoing hydrogen therapy experienced heart failure. However, it's crucial to note that this trial involved intravenous hydrogen saline in hospitalised patients recovering from acute ischemic stroke. Cardiac arrest can occur after an ischemic stroke due to the death of cardiac and neural cells in the post-stroke brain.

According to data 10 from 9,019 patients following acute ischemic stroke, 352 individuals (3.9%) experienced cardiac arrest. In the trial involving 38 patients receiving intravenous hydrogen saline therapy, statistically, one or two participants (3.9% of 38) were expected to experience cardiac arrest based on this data.


Molecular Hydrogen Water And CancerWoman That Has Cancer With No Hair

Another report states adverse event involved "minor events" that "spontaneously resolved" in patients with stage 3 and stage 4 cancer, without specifying the exact nature or frequency of these events.

While ambiguous, this area warrants further investigation, as one hypothesis suggests that hydrogen-induced ghrelin excretion may increase cancer risk. However, no such adverse events have been reported in human or animal models, and current evidence points to molecular hydrogen as a potentially beneficial adjuvant therapy for various cancer models.

This evidence may be complicated by a case study where hydrogen therapy demonstrated a pseudo-progression followed by remission, similar to PD-1 treatment.

Additionally, a biphasic response to molecular hydrogen has been observed in an exercise model, where oxidative stress initially increased during exercise but then aggressively decreased, promoting a harmonious redox state. This phenomenon may also have occurred during a short trial using hydrogen inhalation for Parkinson's Disease, where oxidative stress initially increased.

Molecular hydrogen gas expert Tyler W. LeBaron, founder of Molecular Hydrogen Institute (MHI) - the leaders in molecular hydrogen gas education & research has written a lot on this subject and has proposed that H2 works like a redox adaptogen and promotes beneficial hormesis


Molecular Hydrogen Water And HeartburnOld Man With Heartburn

While a report cited potential heartburn as a gastrointestinal issue in a trial involving molecular hydrogen water, this is highly unlikely to be related to the molecular hydrogen gas itself. In fact, a placebo-controlled trial involving 84 participants over 3 months demonstrated that molecular hydrogen water can improve outcomes for gastroesophageal reflux disease (GERD), a condition in which heartburn is a significant symptom.

Additionally, if the data regarding magnesium content in an open-label metabolic syndrome study was inaccurate, it further decreases the likelihood that molecular hydrogen water contributed to heartburn, as magnesium is commonly used as a treatment for heartburn relief.


Molecular Hydrogen Water And HypoglycaemiaA Old Man With Hypoglycaemia Receiving Treatment

This study showed a diabetic patient experienced hypoglycaemia (low blood sugar) after consuming molecular hydrogen water. However, this was resolved by adjusting insulin levels, suggesting a potential benefit rather than a side effect. This aligns with early clinical research indicating that molecular hydrogen therapy can lower insulin levels in overweight individuals.

Furthermore, hydrogen water has demonstrated promising results in improving insulin sensitivity in participants with non-alcoholic fatty liver disease.

Another study shows a 24-week, double-blind, placebo-controlled trial involving 60 participants showed significant improvements showing potential benefits for metabolic syndrome, a pre-diabetic state.


Molecular Hydrogen Water And Loose StoolsWoman with Belly Pains Due To Loose Stool

In an open-label metabolic syndrome study that recorded most adverse events, 3 participants reported loose stool. And 1 participant reporting and increase in frequency of bowl movement. The study stated "These adverse events having “possible” relationship to the test article were classified as mild in intensity. There were no serious adverse events which occurred during the study."


The Safety Of Molecular Hydrogen Water

Molecular hydrogen water is safe. The process of infusing water with hydrogen gas does not introduce harmful substances, and hydrogen itself is a non-toxic gas. However, when considering its safety it's essential to rely on PEM/SPE technology, scientific evidence and expert opinions.

 Hydrogen Water In A Glass


Molecular hydrogen water exhibits an exceptional safety profile with minimal reported side effects across numerous clinical trials involving thousands of participants. While isolated incidents have been documented, the available evidence strongly suggests that consuming molecular hydrogen water is safe and unlikely to cause adverse reactions.

Other Reputable Sources On Molecular Hydrogen Water

Credible sources like the Molecular Hydrogen Institute (MHI), National Center for Biotechnology Information (NCBI), Research Gate, American Society for Clinical Pharmacology & Therapeutics (ASCPT), Dove Press, and WebMD host a wealth of research articles and studies exploring this topic in-depth.


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